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IFN gamma
英文名：IFNG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114432-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | IFNG antibody, IFG antibody, IFI antibody, Interferon gamma antibody, Immune interferon antibody |
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| 产品参数 | 【产品介绍】Interferons (IFNs) plays a crucial role
in antiviral, antiproliferative, immunomodulatory, antitumor, and antiparasitic activities by inducing transcription of IFN-stimuated genes (ISGs) through activation of the Jak-STAT pathway. In particular, Interferon gamma (IFN γ), a sole member of the Type II IFN family, is involved in lymphocyte activation and the regulation of lymphocyte subsets (proliferation, differentiation) (1). IFN γ is expressed in activated CD4 Th1 cells, CD8 cells, gamma/delta T cells, and activated NK cells. IFN γ expression is induced by IL-2, TNF-α and IL-12 and suppressed by IL-4, IL-10, and TGF-β (2). IFN γ binds to IFN γ receptor (IFNGR), which stimulates various immuno-responses such as macrophages activation and enhancement of the type I IFNs anti-viral and anti-tumor activities. In immunocompetent host cells, IFN γ protects against tumor development and directs immunogenic phenotype (3). IFN γ has been implicated in various human diseases, such as multiple sclerosis and insulin-dependent diabetes mellitus (4). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:250 - 500 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Molt-4, (B) Jurkat, (C) lymph node, and (D) human kidney lysates using anti-IFN gamma RabMAb (cat. #5302-1). Western blot analysis on 5 ng of IFN gamma recombinant protein using anti-IFN gamma RabMAb (cat. #5302-1). Note: molecular weight of recombinant protein is 17 kDa. Specificity A synthetic peptide corresponding to residues in human IFN gamma was used as an immunogen. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR1108 【用途】WB , ICC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】20-25kDa |
| 贮存 | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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