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LCK/p56
英文名：LCK/p56
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114488-100ul | 现货 | 0 | ￥0 |
| 别 名 | LCK antibody, LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, Tyrosine-protein kinase Lck antibody, Lymphocyte cell-specific protein-tyrosine kinase antibody, Protein YT16 antibody, Proto-oncogene Lck antibody, T cell-specific protein-tyro |
| Cas号 | |
| M D L | |
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| 分子量 | |
| 产品参数 | 【产品介绍】The human T-cell or lymphocyte specific
gene Lck/p56 is a member of the Src family of non-receptors tyrosine kinase. Mostly expressed in T cells, Lck has been shown to be critical for the normal development of T lymphocytes (1). Additionally, the N-terminal region of the tyrosine kinase Lck interacts with the cytoplasmic domains of CD4 and CD8 (2). Autophosphorylation at Tyr-394 appears to be required for maximum catalytic activity (3) but it can also be suppressed by phosphorylation of the carboxyl-terminal tyrosine Tyr-505 (4). Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:1,000 IHC: 1:250-500 ICC: 1:100 IP: 1:200 FC: 1:20 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on Jurkat cell lysate using anti-Lck/p56 RabMAb (catalog #1515-1), dilution 1:1,000. B. Immunohistochemical analysis of paraffin-embedded human lymphoma using anti-Lck/p56 RabMAb (catalog #1515-1). Specificity A synthetic peptide corresponding to residues before SH3 domain of human Lck was used as immunogen. The antibody does not cross-react with other SRC family member. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】Y123 【用途】WB , IHC , ICC , FC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】56kDa |
| 贮存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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