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IL-10
英文名:IL10
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检测信息查询

货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308114439-100ul | 现货 | 0 | ¥0 |
别 名 | IL10 antibody, CSIF antibody, IL-10 antibody, IL10A antibody, MGC126450 antibody, MGC126451 antibody, TGIF antibody, Interleukin-10 antibody, Cytokine synthesis inhibitory factor antibody |
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产品参数 | 【产品介绍】Interleukin (IL)-10 is a cytokine that
inhibits production of other regulatory factors, including interferon gamma (IFN-gamma) and IL-2. A dimer of IL-10 is present in solution and is presumed to participate in receptor binding (1). IL-10 is a natural endogenous immunosuppressive cytokine that has been identified in human, murine, and other organisms. Human IL-10 (hIL-10) has high homology with murine IL-10 (mIL-10) as well as with an Epstein-Barr virus genome product BCRFI (2). IL-10 displays pleiotropic immunoregulatory properties. Human and murine IL-10 have a high amino acid sequence identity (ca. 73%) which includes the conservation of all four cysteine residues in human IL-10 and the first four out of five cysteine residues for murine IL-10. IL-10 is a highly alpha-helical protein containing two disulfide bonds, either one or both of which are critical for its structure and function (3). Recommended Applications WB, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:50 - 100 IP: 1:10 - 100 FC: 1:100 - 500 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) THP-1 treated with LPS, (B) THP-1, and (C) Ramos cell lysates using anti-IL-10 RabMAb (cat. #5339-1). Western blot analysis on 5 ng of IL-10 recombinant protein using anti-IL-10 RabMAb (cat. #5339-1). Flow cytometric analysis of permeabilized HeLa cells using anti-IL-10 RabMAb (red) (catalog # 5339-1) or a rabbit IgG (negative) (green). Specificity A synthetic peptide corresponding to residues in human IL-10 was used as an immunogen. |
性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】EPR1114 【用途】WB , ICC , FC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】18kDa |
贮存 | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |