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生化科研试剂 >> 抗体产品 >> 内参抗体 |
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Alpha-Actinin 1 Alpha-Actinin 1 |
货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
1227178915 |
Alpha-Actinin 1 |
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100ul |
3575元 |
现货 |
3天 |
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性 状: |
【产品类型】Rabbit Monoclonal IgG 【反应特异性】Human , Mouse 【克隆 ID】EP2528Y 【用途】WB , ICC , FC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】100 kDa |
质量标准: |
【产品介绍】Alpha-actinin is a ubiquitously expressed protein found in numerous actin structures. It consists of an N-terminal actin binding domain, a central rod domain, a n d a C-terminal domain a n d functions as a homodimer to cross-link actin filaments. The rod domain determines the distance between cross-linked actin filaments a n d also serves as an interaction site f o r several cytoskeletal a n d signaling proteins (1). Alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. Alpha-actinin-1 a n d -4 (ACTN1, ACTN4) are non-muscle isof o r ms version of ACTN. These isof o r m are commonly expressed in filopodia, lamellipodia, stress fibers, sites of adhesion a n d intercellular contacts (2).Recommended Applications WB, ICC, FC, IP Applications and Recommended Dilution Factors WB: 1:500 - 1000 ICC: 1:100-250 FC: 1:40 IP: 1:40 Species Reactivity * Human * *Cross reactivity for this product was determined by western blot. Products Data A. Western blot analysis on (A) NIH 3T3 (B) human skeletal muscle tissue (C) human heart tissue lysates using anti-alpha-actinin 1 RabMAb (cat.# 2358-1), dilution 1:1000. Specificity A synthetic peptide corresponding to residues on the C-terminus of human Alpha-Actinin 1 was used as an immunogen.
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贮 存: |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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