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Fibrinogen beta chain (FGB)
英文名：Rabbit Monoclonal Antibody
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| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113586-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | FGB antibody, MGC104327 antibody, MGC120405 antibody, Fibrinopeptide B antibody, antibody |
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| 产品参数 | 【产品介绍】Fibrinogen beta chain yields monomers
that polymerize into fibrin and acting as a cofactor in platelet aggregation. Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. Defects in FGB are a cause of thrombophilia. Defects in FGB are a cause of congenital afibrinogenemia. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen (1). Recommended Applications WB, ICC, FC Applications and Recommended Dilution Factors WB: 1:1000 - 2000 ICC: 1:100 - 250 FC: 1:20 Species Reactivity * Human, Rat *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on (A) Human plasma (B) Human prostrate and (C) Rat platelet lysates using anti-Fibrinogen beta chain (cat. #2616-1). B. Immunofluorescent staining of HeLa cells using anti-Fibrinogen beta chain RabMAb (cat. #2616-1). Specificity A synthetic peptide corresponding to residues near the C-terminus of in human Fibrinogen beta chain was used as an immunogen. |
| 性状 | 【反应特异性】Human , Rat
【克隆 ID】EPR3083 【用途】WB , ICC , FC 【抗原分子量】56kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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