DOCK2

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 DOCK2 antibody, FLJ46592 antibody, KIAA0209 antibody, Dedicator of cytokinesis protein 2 antibody, antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】DOCK2 is a hematopoietic cell-specific
CDM family protein that is indispensable for
lymphocyte chemotaxis (1). DOCK2 plays a critical role
in lymphocyte homing and immunological synapse formation
by regulating the actin cytoskeleton. It has been shown
that DOCK2 deficiency enables long-term survival of
cardiac allografts across a complete mismatch of the
major histocompatibility complex molecules. DOCK2
is critical for CD28-mediated Rac activation and is
required for the full activation of alloreactive T cells (2).


Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:50 - 100
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) Jurkat and (B) Raji
cell lysates using anti-DOCK2 RabMAb (cat. #5351-1).

Immunohistochemical analysis of paraffin-embedded human
lung tissue using anti-DOCK2 RabMAb (cat. #5351-1).
Note. Positive staining of peripheral lymphocytes

Specificity

A synthetic peptide corresponding to residues near
the C-terminus of human DOCK2 was used as an immunogen.
性状 【反应特异性】Human
【克隆 ID】EPR6647
【用途】WB , IHC
【抗原分子量】212kDa
贮存 Storage Condition and Buffer Store at -20° C. Buffer: PBS (pH 7.2), 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt.
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