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DDIT4 / REDD-1
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113507-100ul | 现货 | 0 | ￥0 |
| 别 名 | DDIT4 antibody, Dig2 antibody, FLJ20500 antibody, REDD-1 antibody, REDD1 antibody, RP11-442H21.1 antibody, RTP801 antibody, DNA damage-inducible transcript 4 protein antibody, HIF-1 responsive protein RTP801 antibody, Protein regulated in development and |
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| 产品参数 | 【产品介绍】DDIT4 / REDD-1 is a transcriptional target
of p53 induced following DNA damage. It functions in the regulation of reactive oxygen species (ROS), which is involved in p63-mediated regulation of epithelial differentiation (1). DDIT4 / REDD-1 inhibits mTOR kinase activity in non-muscle and muscle cells downstream of Akt/PKB and upstream of TSC2. As a stress responsive negative regulator of mTOR signaling, it is implicated in controlling skeletal muscle size (2). Studies show either a pro- or an anti-apoptotic role during the stress response, depending on the cell context (3). Furthermore, DDIT4 / REDD-1 is essential for hypoxia regulation of TORC1 activity (4). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Jurkat, (B) 293T, and (C) K562 cell lysates using anti-DDIT4 / REDD-1 RabMAb (cat. #5144-1). Specificity A synthetic peptide corresponding to residues in human DDIT4 / REDD-1 was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR4037(2) 【用途】WB , ICC 【抗原分子量】35kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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