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Cytokeratin 6 (KRT6A)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113491-100ul | 现货 | 0 | ￥0 |
| 别 名 | KRT6A antibody, CK6A antibody, CK6C antibody, CK6D antibody, K6A antibody, K6C antibody, K6D antibody, KRT6C antibody, KRT6D antibody, Keratin, type II cytoskeletal 6A antibody, Type-II keratin Kb6 antibody |
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| 产品参数 | 【产品介绍】The human type II Cytokeratin 6 (CK6; 56 kDa)
is expressed in a heterogeneous array of epithelial tissues under normal conditions, but is better known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or abnormal differentiation. It has been demonstrated that CK6 isoform, CK6a, is clearly the dominant CK6 isoform in skin tissue samples and cultured epithelial cell lines and that the various isoforms are differentially regulated within and between epithelial tissue types (1). The murine genome is known to have two keratin 6 (CK6) genes, mouse CK6, CK6a and MK6b. These genes display a complex expression pattern with constitutive expression in the epithelia of oral mucosa, hair follicles, and nail beds (2). Pachyonychia congenital (PC) is characterized by hypertrophic nail dystrophy and associated ectodermal features. PC-1 subtype is associated with mutations in keratins 6a or 16, whereas PC-2 subtype is linked to mutations in keratins 6b or 17 (3). Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:100 - 250 IP: 1:30 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on A431 lysate using anti-Cytokeratin 6 RabMAb (cat. # 1951-1), dilution 1:100,000 B. Immunohistochemical staining of paraffin-embedded human squamous cervical carcinoma using anti-Cytokeratin 6 RabMAb (cat. #1951-1). C. Immunofluorescent staining of A431 cells using anti-Cytokeratin 6 RabMAb (cat. #1951-1). Specificity A synthetic peptide corresponding to residues on the C-terminus of human Cytokeratin 6 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR1603Y 【用途】WB , IHC , ICC , IP 【抗原分子量】60kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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