CBFb (CBFB)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 CBFB antibody, PEBP2B antibody, Core-binding factor subunit beta antibody, SL3-3 enhancer factor 1 subunit beta antibody, SL3/AKV core-binding factor beta subunit antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】CBFb is the beta subunit of a
heterodimeric core-binding transcription factor belonging
to the PEBP2/CBF transcription factor family that
master-regulates a host of proteins specific
to hematopoiesis (e.g., RUNX1) and osteogenesis
(e.g., RUNX2). The beta subunit is a non-DNA
binding regulatory subunit; it allosterically enhances
DNA binding by alpha subunit as the complex binds to
the core site of various enhancers and promoters,
including murine leukemia virus, polyomavirus
enhancer, T-cell receptor enhancers and GM-CSF promoters (1).


Recommended Applications

WB, IHC, ICC, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
FC: 1:100 - 500
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.


Products Data

Western blot analysis on (A) K562, (B) HUVEC, and (C)
Jurkat cell lysates using anti-CBFb RabMAb (cat. #5421-1).

Immunohistochemical analysis of paraffin-embedded
human breast tissue using anti-CBFb RabMAb (cat.# 5421-1).


Specificity

A synthetic peptide corresponding to residues in human
CBFb was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6322
【用途】WB , IHC , ICC , FC
【抗原分子量】21kDa
贮存 Storage Condition and Buffer Store at -20° C. Buffer: PBS (pH 7.2), 50% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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