ADAM15

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 ADAM15 antibody, MDC15 antibody, Disintegrin and metalloproteinase domain-containing protein 15 antibody, Metargidin antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】ADAM15 is a member of the ADAM (a
disintegrin and metalloproteinase) protein family.
ADAM family members are type I transmembrane
glycoproteins known to be involved in cell adhesion
and proteolytic ectodomain processing of cytokines
and adhesion molecules. ADAM15 contains multiple
functional domains including a zinc-binding
metalloprotease domain, a disintegrin-like domain, as
well as a EGF-like domain. Through its
disintegrin-like domain, it specifically interacts with
the integrin beta chain, beta 3. It also interacts with
Src family protein-tyrosine kinases in a
phosphorylation-dependent manner, suggesting that ADAM15
may function in cell-cell adhesion as well as in
cellular signaling (1).


Recommended Applications

WB, IHC, IP
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:250 - 500
IP: 1:10 - 100
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data
Western blot analysis on SW480 cell lysate using
anti-ADAM15 RabMAb (cat. #5135-1).
Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-ADAM15 RabMAb (cat.# 5135-1).

Specificity

A synthetic peptide corresponding to residues in
the extracellular domain in human ADAM15 was used as
an immunogen.
性状 【反应特异性】Human
【用途】WB , IHC , IP
【抗原分子量】110 (pro-ADAM15) / 90 kDa (mature)
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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