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ACO1
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113306-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | ACO1 antibody, ACONS antibody, IREB1 antibody, IREBP antibody, IREBP1 antibody, IRP1 antibody, Cytoplasmic aconitate hydratase antibody, Iron-responsive element-binding protein 1 antibody |
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| 产品参数 | 【产品介绍】Aconitase 1, also known as iron
regulatory element binding protein 1 (IREB1) or ACO1, is a cytosolic protein that binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. ACO1 was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes (1). Recommended Applications WB, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 IP: 1:10 - 100 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) human thyroid, (B) HeLa, (C) fetal kidney, (D) HepG2, and (E) T.T. lysates using anti-ACO1 RabMAb (cat. #5505-1). Immunofluorescent staining of HeLa cells using anti-ACO1 RabMAb (cat. #5505-1). Specificity A synthetic peptide corresponding to residues in human ACO1 was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR7225
【用途】WB , ICC , IP 【抗原分子量】98kDa |
| 贮存 | Storage Condition and Buffer Store at -20° C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. |
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