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Recombinant Human Angiogenin
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性状 | Recombinant Human Angiogenin 是一种心血管生成的诱导剂。Angiogenin可能有助于胶质瘤的恶性转化以及血管生成过程。
Synonyms rHuAngiogenin; ANG; RNASE5; Angiogenin ; 重组人血管生成素 Species Human Source E. coli Accession P03950 Gene ID 283 Molecular Weight Approximately 14.0 kDa AA Sequence QDNSRYTHFL TQHYDAKPQG RDDRYCESIM RRRGLTSPCK DINTFIHGNK RSIKAICENK NGNPHRENLR ISKSSFQVTT CKLHGGSPWP PCQYRATAGF RNVVVACENG LPVHLDQSIF RRP Biological Activity Data is not available. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM PBS, 150 mM NaCl, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Angiogenin (rHuAngiogenin) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Angiogenin (rHuAngiogenin) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Angiogenin (Ang) is one of the members of the pancreatic ribonuclease (RNase) superfamily that have unusual biological properties. The amino acid sequence of angiogenin revealed that it was homologous to RNase A. It shares 33% sequence identity with the bovine enzyme, including counterparts to the two histidines and one lysine that constitute the catalytic active site. It belongs to the pancreatic RNase superfamily of proteins and is specifically endocytosed by endothelial cells and transported to the nucleus, where it accumulates in the nucleolus. |
贮存 |
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