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Recombinant Human PD-L1, His (HEK293-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132914-50 μg 0 ￥5900 请登录
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1308132914-100 μg 0 ￥10400 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human PD-L1, His (HEK293-expressed) 在妊娠、组织移植、自身免疫性疾病和肝炎等疾病状态下，对免疫系统的适应性起着重要的抑制作用。
Synonyms
rHuPD-L1, His; Programmed death ligand 1; CD274; B7-H1 ; 重组人 PD-L1, His (HEK293 表达)
Species
Human

Source
HEK 293

Accession
Q9NZQ7

Gene ID
29126

Molecular Weight
31-35 kDa

AA Sequence
FTVTVPKDLY VVEYGSNMTI ECKFPVEKQL DLAALIVYWE MEDKNIIQFV HGEEDLKVQH SSYRQRARLL KDQLSLGNAA LQITDVKLQD AGVYRCMISY GGADYKRITV KVNAPYNKIN QRILVVDPVT SEHELTCQAE GYPKAEVIWT SSDHQVLSGK TTTTNSKREE KLFNVTSTLR INTTTNEIFY CTFRRLDPEE NHTAELVIPE LPLAHPPNER THHHHHH

Biological Activity
2 µg/mL (100 µL/well) of immoblized recombinant human PD-L1-His can bind human PD-1-Fc with a linear range of 24-390 ng/mL.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, 5% trehalose and mannitol.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human PD-L1, His (HEK293-expressed) (rHuPD-L1, His) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human PD-L1, His (HEK293-expressed) (rHuPD-L1, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Programmed death-ligand 1 (PD-L1) has been speculated to play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Normally the adaptive immune system reacts to antigens that are associated with immune system activation by exogenous or endogenous danger signals[1].
贮存
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
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