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Recombinant Rat Fractalkine/CX3CL1 (HEK293-expressed)

英文名：
Cas号：
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1308132868-10 μg 0 ￥3800 请登录
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1308132868-50 μg 0 ￥9200 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Rat Fractalkine/CX3CL1 (HEK293-expressed) 是 CX3C 趋化因子家族的成员，与多种肿瘤有关，促进肿瘤进展。
Synonyms
rRtFractalkine/CX3CL1; Fractalkine; CX3CL1; FKN; SCYD1; Neurotactin; NTT ; 重组大鼠趋化因子/CX3CL1 (HEK293 细胞表达)
Species
Rat

Source
HEK 293

Accession
O55145

Gene ID
89808

Molecular Weight
70-90 kDa

AA Sequence
QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNGGKFE KRVDNVTPRI TSATRGLSPT ALAKPESATV EDLTLEPTAI SQEARRPMGT SQEPPAAVTG SSPSTSKAQD AGLAAKPQST GISEVAAVST TIWPSSAVYQ SGSSLWAEEK ATESPPTIAL STQASTTSSP KQNVGSEGQP PWVQEQDSTP EKSPGPEETN PVHTDIFQDR GPGSTVHPSV APTSSEKTPS PELVASGSQA PKVEEPIHAT ADPQKLSVFI TPVPDSQAAT

Biological Activity
The EC50 is <1 µg/mL as measured on Ca2+ mobilization assay in CHO-K1/Gα15/rCX3CR1 cells (human Gα15 and rat CX3CR1 stably expressed in CHO-K1 cells).

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Rat Fractalkine/CX3CL1 (HEK293-expressed) (rRtFractalkine/CX3CL1) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Rat Fractalkine/CX3CL1 (HEK293-expressed) (rRtFractalkine/CX3CL1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Fractalkine is the only member of the CX3C chemokine family so far. It is expressed in many cell types such as hematopoietic cells, endothelial cells, epithelial cells, smooth muscle cells, dendritic cells, neurons, and fibroblasts. Fractalkine exists in two forms that have distinct cellular functions. The soluble form is a chemoattractant for cells expressing the CX3CR1 receptor. The membrane-bound form functions as an adhesion molecule that promotes adhesion and migration[1].
贮存
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