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Recombinant Mouse April/TNFSF13

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132831-10 μg 0 ￥4200 请登录
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1308132831-50 μg 0 ￥12400 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Mouse April/TNFSF13 是肿瘤坏死因子 (TNF) 配体家族成员，分子量为 21.9 kDa。
Synonyms
rMuApril/TNFSF13; TNFSF 13; TNFSF-13; CD256
Species
Mouse

Source
E. coli

Accession
Q9D777

Gene ID
69583

Molecular Weight
Approximately 21.9 kDa

AA Sequence
MRREVSRLQR SGGPSQKQGE RPWQSLWEQS PDVLEAWKDG AKSRRRRAVL TQKHKKKHSV LHLVPVNITS KDSDVTEVMW QPVLRRGRGL EAQGDIVRVW DTGIYLLYSQ VLFHDVTFTM GQVVSREGQG RRETLFRCIR SMPSDPDRAY NSCYSAGVFH LHQGDIITVK IPRANAKLSL SPHGTFLGFV KL

Biological Activity
Full biological activity determined by its ability to induce cell proliferation of RPMI 8226 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against 20 mM acetic acid.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Mouse April/TNFSF13 (rMuApril/TNFSF13) to 100 µg/mL using ddH2O.

Storage & Stability
Lyophilized recombinant Mouse April/TNFSF13 (rMuApril/TNFSF13) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
The TNFSF13 gene is located at chromosomal region 17p13.1 and is expressed in various tissues and organs including heart muscle. TNFSF13 is a regulator of the development and function of B cells. TNFSF13 has important roles in normal immune responses, and also in the development of autoimmune and inflammatory diseases. Plasma levels of TNFSF13 are reported to be increased in patients with multiple sclerosis, Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis. The levels of TNFSF13 are also demonstrated to be significantly higher in the synovial fluid of patients with rheumatoid arthritis than in the serum, suggesting that this protein may be produced locally at the site of inflammation[1].
贮存
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