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Recombinant Human TECK/CCL25

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132802-10 μg 0 ￥3200 请登录
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1308132802-50 μg 0 ￥7800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human TECK/CCL25 参与T细胞的发育和细胞迁移小肠的过程。
Synonyms
rHuTECK/CCL25; C-C motif chemokine 25; SCYA25 ; 重组人 CC 趋化因子25
Species
Human

Source
E. coli

Accession
O15444

Gene ID
6370

Molecular Weight
Approximately 14.3 kDa

AA Sequence
MQGVFEDCCL AYHYPIGWAV LRRAWTYRIQ EVSGSCNLPA AIFYLPKRHR KVCGNPKSRE VQRAMKLLDA RNKVFAKLHH NTQTFQAGPH AVKKLSSGNS KLSSSKFSNP ISSSKRNVSL LISANSGL

Biological Activity
Full biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 150 mM NaCl.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human TECK/CCL25 (rHuTECK/CCL25) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Human TECK/CCL25 (rHuTECK/CCL25) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Thymus-expressed chemokine (TECK) or CCL25, a CC chemokine expressed predominantly in thymus and epithelium of the small intestine and a ligand of CCR9, mediates chemotaxis of CCR9-bearing T cells. CCL25 is the predominant chemokine involved in cellular migration to the small intestine[1]. CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa[2].
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