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Recombinant Human NGF Receptor

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132783-10 μg 0 ￥3200 请登录
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1308132783-50 μg 0 ￥7000 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human NGF Receptor (HEK293-expressed) 是一种肿瘤坏死因子受体亚家族中的一员，在头颈部鳞状细胞癌等多种恶性肿瘤中作为具有肿瘤起始能力的细胞标志物。
Synonyms
rHuNGFR; Gp80-LNGFR; p75 ICD; CD271; TNFRSF16 ; 从组人 NGF 受体 (HEK293 表达)
Species
Human

Source
HEK 293

Accession
P08138

Gene ID
4804

Molecular Weight
32-60 kDa

AA Sequence
KEACPTGLYT HSGECCKACN LGEGVAQPCG ANQTVCEPCL DSVTFSDVVS ATEPCKPCTE CVGLQSMSAP CVEADDAVCR CAYGYYQDET TGRCEACRVC EAGSGLVFSC QDKQNTVCEE CPDGTYSDEA NHVDPCLPCT VCEDTERQLR ECTRWADAEC EEIPGRWITR STPPEGSDST APSTQEPEAP PEQDLIASTV AGVVTTVMGS SQPVVTRGTT DN

Biological Activity
The ED50 is <0.4 μg/mL as measured by TF-1 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human NGF Receptor (HEK293-expressed) (rHuNGFR) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human NGF Receptor (HEK293-expressed) (rHuNGFR) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
NGFR, also known as p75 neurotrophin receptor (p75NTR) and CD271, is a cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. There are two general classes of neurotrophin receptors: the high-affinity nerve growth factor tyrosine kinase receptors Trk A, B and C (encoded by NTRK1, NTRK2, and NTRK3, respectively) and the low-affinity nerve growth factor receptor NGFR. NGFR has been identified as a marker of cells with tumor-initiating capacity in multiple malignancies, including head and neck squamous cell carcinoma[1].
贮存
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