Recombinant Human Epigen (CHO-expressed)

英文名:
Cas号:
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Cas号
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分子式
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产品参数
性状 Recombinant Human Epigen (CHO-expressed) 是一种表皮生长因子,对只表达 ErbB-2 的细胞没有刺激作用,在表达 ErbB-1, 共表达 ErbB-2 和其他 ErbB 的细胞中,作为细胞分裂素能够促进细胞有丝分裂。
Synonyms
rHuEpigen; Epithelial mitogen; EPG ; 重组人 Epigen 因子 (CHO 细胞表达)
Species
Human

Source
CHO

Accession
Q6UW88

Gene ID
255324

Molecular Weight
15-20 kDa

AA Sequence
AVTVTPPITA QQGNWTVNKT EADNIEGPIA LKFSHLCLED HNSYCINGAC AFHHELEKAI CRCFTGYTGE RCEHLTLTSY A

Biological Activity
The ED50 is <1 μg/mL as measured by 3T3 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Epigen (CHO-expressed) (rHuEpigen) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human Epigen (CHO-expressed) (rHuEpigen) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Recombinant Human Epigen (CHO-expressed) is a EGF-like growth factor that does not stimulate cells singly expressing ErbB-2, but acts as a mitogen for cells expressing ErbB-1 and co-expressing ErbB-2 in combination with the other ErbBs, with potent mitogenic activity[1].
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