Human IgA (heavy chain)

英文名:Human IgA (heavy chain)
Cas号:
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别 名
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Immunoglobulins recognize foreign antigens
and initiate immune responses such as phagocytosis and
the complement system. Each immunoglobulin molecule
consists of two identical heavy chains and two
identical light chains (1). IgA is the major class
of immunoglobulin in secretions: tears, saliva,
colostrum, mucus. Since it is found in secretions,
secretory IgA is important in local (mucosal) immunity.
When IgA is found in secretions, another protein called
the secretory piece or T piece is associated with it.
Unlike the remainder of the IgA that is made in the
plasma cell, the secretory piece is made in epithelial
cells and is added to the IgA as it passes into
secretions. The secretory piece helps IgA to be
transported across the mucosa and also protects it
from degradation in secretions (2).

Recommended Applications
WB, IHC, ICC, IP, ELISA
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:10 - 100
ELISA: 1:250 - 4,000
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) human tonsil, (B) human
plasma, and (C) human spleen lysates using anti-Human
IgA (heavy chain) RabMAb (cat. #5205-1).

Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-Human IgA
(heavy chain) RabMAb (cat. #5205-1).

Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-Human IgA
(heavy chain) RabMAb (cat. #5205-1).

Specificity
A recombinant protein fragment corresponding to human
IgA was used as an immunogen. It does not react with
either kappa or lambda light chain, and it only reacts
with IgA.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR5367
【用途】WB , IHC , ICC , IP , ELISA 【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】50kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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