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Histone H2A.Z

英文名：H2AFZ
Cas号：
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别 名 H2AFZ antibody, H2A.z antibody, H2A/z antibody, H2AZ antibody, MGC117173 antibody, Histone H2A.Z antibody, antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Histones are basic nuclear proteins that
are responsible for the nucleosome structure of
the chromosomal fiber in eukaryotes. Nucleosomes consist
of approximately 146 bp of DNA wrapped around a
histone octamer composed of pairs of each of the four
core histones (H2A, H2B, H3, and H4). The chromatin fiber
is further compacted through the interaction of a
linker histone, H1, with the DNA between the nucleosomes
to form higher order chromatin structures. Histone H2A.Z
is a replication-independent member of the histone
H2A family that is distinct from other members of
the family. Studies in mice have shown that this
particular histone is required for embryonic development
and indicate that lack of functional histone H2A leads
to embryonic lethality (1).

Recommended Applications
WB, IHC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:250 - 500
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) C6, (B) Raw 264.7,
(C) PC-12, (D) NIH/3T3, (E) HeLa, (F) HepG2, and (G)
human thymus lysates using anti-Histone H2A.Z RabMAb (cat. #5338-1).

Immunohistochemical analysis of paraffin-embedded
human breast tissue using anti-Histone H2A.Z RabMAb
(cat. #5338-1).

Specificity
A synthetic peptide corresponding to residues near
the C-terminus of human Histone H2A.Z was used as
an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6172
【用途】WB , IHC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】14kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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