Beta-Tubulin

英文名:Beta-Tubulin
Cas号:
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
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别 名 TUBB, TUBB5, Tubulin beta chain, Tubulin beta-5 chain
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Microtubules are essential parts in
eukaryotic cell structures, transportation, and mitosis
and consists mainly of 2 soluble protein subunits, alpha
and beta tubulin. Beta-tubulin binds to alpha tubulin
to form tubulin heterodimer which is
posttranslationally modified (1). The tubulin dimer
complex binds to GTP and assembles onto the positive ends
of microtubules. After incorporation into the
microtubules, bound GTP is hydrolyzed by beta tubulin.
The stability of the dimer in the microtubules is
depended on presence of beta tubulin, where dimer with
GTP bound beta-tubulin is stable to
microtubule incorporation (2). Mutation on beta-tubulin
has been linked to anti-cancer drug resistance in
lung cancers (3).

Recommended Applications
WB, IHC, ICC, FC
Applications and Recommended Dilution Factors

WB IHC ICC FC IP
1:1,000 - 10,000 1:250 - 500 1:100 - 250 1:10 - 100

Species Reactivity*

Human Mouse Rat
Positive Positive Positive

Product Data

Western blot analysis on (A) MCF-7, (B) Jurkat, (C)
Ramos, and (D) HeLa cell lysates using anti-Beta-
Tubulin RabMAb (cat. # 3124-1).

Immunohistochemical analysis of paraffin-embedded
human brain tissue using anti-Beta-Tubulin RabMAb
(cat. # 3124-1).

Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-Beta-Tubulin RabMAb
(cat. # 3124-1).

Immunofluorescent staining of HeLa cells using
anti-Beta-Tubulin RabMAb (cat. # 3124-1).

Specificity
A synthetic peptide corresponding to residues in
human Beta-Tubulin was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR1330
【用途】WB , IHC , ICC , FC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】50 kDa
贮存 Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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