GnRHR (GNRHR)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 GNRHR antibody, GNRHR1 antibody, GRHR antibody, LHRHR antibody, LRHR antibody, Gonadotropin-releasing hormone receptor antibody, antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】GnRHR is the receptor for type 1
gonadotropin-releasing hormone. This receptor is a member
of the seven-transmembrane, G-protein coupled
receptor (GPCR) family. It is expressed on the surface
of pituitary gonadotrope cells as well as
lymphocytes, breast, ovary, and prostate. Following
binding of gonadotropin-releasing hormone, the
receptor associates with G-proteins that activate
a phosphatidylinositol-calcium second messenger
system. Activation of GnRHR ultimately causes the release
of gonadotropic luteinizing hormone (LH) and
follicle stimulating hormone (FSH). Defects in GnRHR are
a cause of hypogonadotropic hypogonadism (HH) (1).


Recommended Applications

WB, IHC, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:250 - 500
ICC: 1:100 - 250
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) SH-SY5Y, (B) NIH:OVCAR-3,
(C) MCF-7, (D) PC-3, and (E) fetal brain lysates
using anti-GnRHR RabMAb (cat. #5348-1).

Immunohistochemical analysis of paraffin-embedded
human testis tissue using anti-GnRHR RabMAb (cat.# 5348-1).

Specificity

A synthetic peptide corresponding to residues in human
GnRHR was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5293
【用途】WB , IHC , ICC
【抗原分子量】60kDa
贮存 Storage Condition and Buffer Store at -20° C. Buffer: PBS (pH 7.2), 50% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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