GluR6 (GRIK2)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 GRIK2 antibody, EAA4 antibody, GLR6 antibody, GLUK6 antibody, GLUR6 antibody, MGC74427 antibody, MRT6 antibody, Glutamate receptor, ionotropic kainate 2 antibody, Glutamate receptor 6 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Glutamate receptors are the
predominant excitatory neurotransmitter receptors in
the mammalian brain and are activated in a variety of
normal neurophysiologic processes. GluR6 belongs to
the kainate family of glutamate receptors, which
are composed of four subunits and function as
ligand-activated ion channels. It is subject to RNA
editing at multiple sites within the first and
second transmembrane domains, which is thought to alter
the structure and function of the receptor
complex. Mutations in GluR6 have been associated
with autosomal recessive mental retardation (1).


Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:250 - 500
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) fetal brain, (B) human
kidney, and (C) A431 lysates using anti-GluR6 RabMAb
(cat. #5201-1).

Immunohistochemical analysis of paraffin-embedded
human brain tissue using anti-GluR6 RabMAb (cat. #5201-1).

Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-GluR6 RabMAb (cat. #5201-1).

Immunohistochemical analysis of paraffin-embedded
human kidney tissue using anti-GluR6 RabMAb (cat. #5201-1).

Specificity

A synthetic peptide corresponding to residues in
the extracellular domain of human GluR6 was used as
an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6307
【用途】WB , IHC
【抗原分子量】103kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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