FOXP3

英文名:Rabbit Monoclonal Antibody
Cas号:
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货号 规格 货期 库存 价格 会员价 订购
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别 名 FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, MGC141961 antibody, MGC141963 antibody, PIDX antibody, XPID antibody, Forkhead box protein P3 antibody, Scurfin antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】FOXP3 is a forkhead-winged helix
transcription factor involved in immune function, and
its expression has been used to define
CD4+CD25+FOXP3+ suppressive regulatory T cells (Treg)
(1). It has emerged as the most definitive marker for
Treg, and it is thus crucial to thymic development
and peripheral function (1). FOXP3 has been proven to
be associated with immunoregulation, autoimmune
diseases, infections, and tumor immune evasion/escape
(2). Defects in FOXP3 are the cause of
immunodeficiency polyendocrinopathy; enteropathy;
and X-linked syndrome (IPEX), also known as
X-linked autoimmunity-immunodeficiency syndrome (3).


Recommended Applications

WB, FC
Applications and Recommended Dilution Factors

WB: 1:1,000-10,000
FC: 1:10 - 100
Species Reactivity

Human, Mouse, Rat

Products Data

Western blot analysis on (A) fetal brain, (B) HeLa,
(C) 293T, (D) A375, (E) human spleen, (F) peripheral
blood mononuclear cells (PBMC), and (G) IM-9 cell
lysates using anti-FOXP3 RabMAb (cat. # 3100-1).

Specificity

A synthetic peptide corresponding to residues in human
FOXP3 was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR3002(2)
【用途】WB , FC
【抗原分子量】47kDa
贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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