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Estrogen Related Receptor alpha (ERR alpha) (ESRRA)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113561-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | ESRRA antibody, ERR1 antibody, ERRa antibody, ERRalpha antibody, ESRL1 antibody, NR3B1 antibody, Steroid hormone receptor ERR1 antibody, Nuclear receptor subfamily 3 group B member 1 antibody |
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| 产品参数 | 【产品介绍】Estrogen-related receptor alpha (ERR alpha)
is an orphan member of the superfamily of nuclear hormone receptors. ERR alpha was initially isolated based on its sequence homology to the estrogen receptor but is not activated by classic estrogens. Binding site selection experiments show that ERR alpha preferentially binds to an ERR alpha response element (ERRE) containing a single consensus half-site, TNAAGGTCA. Data demonstrate that ERR alpha can control the expression of MCAD through the NRRE-1 and thus may play an important role in regulating cellular energy balance in vivo (1). The estrogen-related receptors ERRalpha and ERRbeta (formerly ERR1 and ERR2) form a subgroup of the steroid/thyroid/retinoid receptor family. ERRalpha and ERRbeta are homologous to the estrogen receptor and bind similar DNA targets; however, they are unable to activate gene transcription in response to estrogens (2). Recommended Applications WB, IP, FC Applications and Recommended Dilution Factors WB: 1:2500 5000 IP: 1:40 FC: 1:20 Species Reactivity * Human, Mouse, Rat *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on HeLa cell lysate using anti-ERR alpha RabMAb (cat. # 2131-1), dilution 1:5000. Specificity A synthetic peptide corresponding to residues near the N-terminus of human ERRalpha was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR46Y 【用途】WB , FC , IP 【抗原分子量】53kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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