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eEF-2K
英文名：Rabbit Monoclonal IgG
Cas号：
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113536-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation fact o r 2 kinase |
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| 产品参数 | 【产品介绍】Eukaryotic elongation fact o r -2
kinase (eEF-2k) previously known as Ca2+/ calmodulin-dependent protein kinase III, is an abundant cytoplasmic protein highly specific f o r elongation fact o r -2 (eEf-2) (1). Phosph o r ylation of eEF-2 by eEF-2 kinase on specific threonine residues results in the inactivation of eEF-2 a n d in termination of mRNA translation (2). The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) a n d insulin, but is also regulated both negatively a n d positively by phosph o r ylation by different protein kinases (AMPK, S6K1, p90 RSK) (3-4). There is also evidence that eEF-2 phosph o r ylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis a n d malignant tum o r s (5-6). WB: 1: 50,000 IP: 1:20 A. Western blot analysis on HeLa (lane A) a n d Jurkat (lane B) using anti- eEF-2K RabMAb (cat. # 1718-1), dilution 1:50,000 |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EP724Y 【用途】WB , IP 【抗原分子量】95 kDa |
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