CSK

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 CSK antibody, MGC117393 antibody, Tyrosine-protein kinase CSK antibody, C-Src kinase antibody, Protein-tyrosine kinase CYL antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】The fundamental regulator of Src signaling
is CSK, which blocks it via tyrosine phosphorylation
(1). The kinase domain of CSK is responsible for
the recognition of the Src family kinases as its
specific substrates, resulting in phosphorylation of
the C-terminal tail. The ability of CSK to regulate
Src kinase activity in vivo also depends on both the SH2
and SH3 domains of CSK. Unlike the Src family kinases,
CSK is not constitutively membrane-localized, and the
SH2 domain is required for the recruitment of CSK to
the plasma membrane (2).


Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:50 - 100
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.
Products Data

Western blot analysis on (A) Jurkat, (B) Ramos, and (C)
RAW 264.7 cell lysates using anti-CSK RabMAb
(cat. #5448-1).

Immunohistochemical analysis
of paraffin-embedded human tonsil tissue using
anti-CSK RabMAb (cat. #5448-1).
Specificity

A synthetic peptide corresponding to residues in human
CSK was used as an immunogen.

性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6771
【用途】WB , IHC
【抗原分子量】50kDa
贮存 Storage Condition and Buffer Store at -20° C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt.
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