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c-Myc DyLight® 488 (MYC)
英文名：Rabbit Monoclonal Antibody
Cas号：
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113456-100ul | 现货 | 0 | ￥0 |
| 别 名 | MYC antibody, MRTL antibody, bHLHe39 antibody, c-Myc antibody, Myc proto-oncogene protein antibody, Proto-oncogene c-Myc antibody, Transcription factor p64 antibody |
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| M D L | |
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| 产品参数 | 【产品介绍】Oncogene-encoded proteins c-Myc, N-Myc,
and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas (1), and the L-Myc gene in human small cell lung carcinomas (2). c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 (3) and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription (3). Recommended Applications ICC Applications and Recommended Dilution Factors ICC: 1:50 - 100 Species Reactivity Human Products Data Immunofluorescent staining of HeLa cells using anti-c-Myc antibody conjugated with Dylight 488 (green, Cat# 4581-1) and Dapi (blue). Specificity A synthetic peptide corresponding to residues in N-terminus of human c-Myc was used as immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】Y69 【用途】ICC 【抗原分子量】57kDa |
| 贮存 | Storage Condition and Buffer Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |
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