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CEACAM1
英文名：Rabbit Monoclonal Antibody
Cas号：
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113442-100ul | 现货 | 0 | ￥0 |
| 别 名 | CEACAM1 antibody, BGP antibody, BGP1 antibody, BGPI antibody, Carcinoembryonic antigen-related cell adhesion molecule 1 antibody, Biliary glycoprotein 1 antibody |
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| 产品参数 | 【产品介绍】Carcinoembryonic antigen-related cell
adhesion molecule (CEACAM) proteins, members of the immunoglobulin (Ig) superfamily, are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (1). CEACAM1 is a type I membrane glycoprotein that plays a role in intercellular adhesion to inhibit tumor development as a bacterial adhesin (2). Moreover, CEACAM1 is an active regulator of cell signaling by modulating the insulin or EGF receptor pathways in epithelial cells or the Zap-70 pathway in hematopoietic cells (2). It is known to be a tumor suppressor, since CEACAM1 is down-regulated in most epithelial cell cancers and T-cell leukemias (3). Recommended Applications WB, IHC Applications and Recommended Dilution Factors WB: 1:1,000-10,000 IHC: 1:100 - 250 Species Reactivity Human Products Data Western blot analysis on (A) HepG2, (B) fetal liver, and (C) A549 cell lysates using anti-CEACAM1 RabMAb (cat. # 2928-1) Immunohistochemical staining of paraffin-embedded human kidney tissue using anti-CEACAM1 RabMAb (cat. #2928-1). Immunohistochemical staining of paraffin-embedded human liver tissue using anti-CEACAM1 RabMAb (cat. #2928-1). Specificity A synthetic peptide corresponding to residues near the N-terminus of human CEACAM1 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR4048 【用途】WB , IHC 【抗原分子量】120-180kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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