CD5 (CD79A)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 CD79A antibody, IGA antibody, MB-1 antibody, B-cell antigen receptor complex-associated protein alpha chain antibody, Ig-alpha antibody, MB-1 membrane glycoprotein antibody, Membrane-bound immunoglobulin-associated protein antibody, Surface IgM-associated
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】CD5 (Lymphocyte antigen T1/Leu-1) is
a transmembrane glycoprotein which has been implicated as
a receptor in the regulation of T-cell proliferation
(1). CD5 is part of the scavenger receptor
cysteine-rich (SRCR) family group B and it is found on
95% of thymocytes and 72% of peripheral blood
lymphocytes. In lymph nodes, the main reactivity is
observed in T cell areas. CD5 is expressed by T
cell leukemia, lymphomas, and activated T
cells. Occasionally, CD5 antigen is also expressed on
a subset of B cells. Mantle cell lymphomas (same as
diffuse centrocytic lymphomas) are CD5+ while the
follicle center cell lymphomas are CD5. A ligand
for CD72/LYB-2, CD5 has been linked to negative
regulation of T cell and B cell receptors signaling (2).


Recommended Applications

WB, IHC
Applications and Recommended Dilution Factors

WB: 1:500
IHC: 1:50-1:100
Species Reactivity *

Human

*Cross reactivity determined by western blot only.


Products Data


A. Western blotting assay using Jurkat cell lysate
with Rabbit anti-CD5 monoclonal antibody
(cat# 4210-1), 1:500 dilution

B. Immunohistochemical staining of paraffin-embedded
human tonsil stained with anti-CD5 RabMAb (Cat.#4210-1)


Specificity

A synthetic peptide from the intracellular region of CD5.

性状 【反应特异性】Human
【克隆 ID】SP19
【用途】WB , IHC
【抗原分子量】58kDa
贮存 Storage Condition and Buffer Store at 2-8° C. Tissue culture supernatant with 0.1% sodium azide and 0.05% BSA. Stable for 12 months from the date of receipt.
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