Bak Rabbit Antibody

英文名:Rabbit Monoclonal IgG
Cas号:
检测信息查询
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别 名 Apoptosis regulat o r BAK, Bcl-2-like 7 protein
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Bak a pro-apoptotic analog to Bax, is a
member of the Bcl-2 family of proteins. During
mitochondria-regulated programmed cell death, Bak
promotes apoptosis by binding Bcl-2 a n d inhibiting
its anti-apoptotic function (1). Upon apoptotic
stimulation, Bak translocates from the cytosol to
the mitochondrial membrane (2). Pro-apoptotic
cascade activates BID, which oligomerizes Bak
into p o r es that result in the release of
cytochrome c (2, 3). In healthy cells, Bak associate
with Bcl-xL a n d Mcl-1 but not with Bcl-2,
Bcl-w o r A1 a n d only when freed of both Bak will
induce apoptosis.


WB: 1:1,000-5,000
IHC: 1:250-500
ICC: 1:250-500
Flow Cytometry: 1:10

A. Western blot analysis on Hela cell lysate using
anti-Bak RabMAb (cat. # 1542-1). dilution 1:5,000.

B. Immunohistochemical analysis of paraffin-embedded
human stomack carcinoma using anti-Bak RabMAb
(cat. # 1542-1).
性状 【反应特异性】Human
【克隆 ID】Y164
【用途】WB , IHC , ICC , FC
【抗原分子量】23 kDa
贮存
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