ATP7B

英文名:Rabbit Monoclonal Antibody
Cas号:
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货号 规格 货期 库存 价格 会员价 订购
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别 名 ATP7B antibody, PWD antibody, WC1 antibody, WD antibody, WND antibody, WND/140 kDa antibody, Copper pump 2 antibody, Wilson disease-associated protein antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】ATP7B is a member of the P-type cation
transport ATPase family and has several
membrane-spanning domains, an ATPase consensus sequence,
a hinge domain, a phosphorylation site, and at least
2 putative copper-binding sites. It functions as a
monomer, exporting copper out of the cells, such as
the efflux of hepatic copper into the bile. Mutations
in ATP7B have been associated with Wilson disease (WD)
(1).


Recommended Applications

WB, ICC, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250
FC: 1:10 - 100
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) Caco-2 and (B) HepG2
cell lysates using anti-ATP7B RabMAb (cat. #5320-1).

Flow cytometric analysis of permeabilized HepG2 cells
using anti-ATP7B RabMAb (red) (catalog # 5320-1) or a
rabbit IgG (negative) (green).

Specificity

A synthetic peptide corresponding to residues on
the C-terminus in human ATP7B was used as an immunogen.
性状 【反应特异性】Human
【克隆 ID】EPR6794
【用途】WB , ICC , FC
【抗原分子量】157kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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