Aromatase (CYP19A1)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 CYP19A1 antibody, ARO antibody, ARO1 antibody, CPV1 antibody, CYAR antibody, CYP19 antibody, MGC104309 antibody, P-450AROM antibody, Cytochrome P450 19A1 antibody, Aromatase antibody, CYPXIX antibody, Cytochrome P-450AROM antibody, Estrogen synthase antib
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Aromatase is a member of the cytochrome
P450 superfamily of enzymes. The cytochrome P450
proteins are monooxygenases that catalyze many
reactions involved in drug metabolism and synthesis
of cholesterol, steroids and other lipids.
Aromatase localizes to the endoplasmic reticulum
and catalyzes the last steps of estrogen biosynthesis,
three successive hydroxylations of the A ring of
androgens. Mutations in Aromatase can result in
either increased or decreased aromatase activity;
the associated phenotypes suggest that estrogen
functions both as a sex steroid hormone and in growth
or differentiation (1).


Recommended Applications

WB, IP, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IP: 1:10 - 100
FC: 1:100 - 500
Species Reactivity *

Human, Rat

*Species cross-reactivity is based on WB analysis.

Products Data
Western blot analysis on (A) human placenta, (B)
human uterus, (C) JAR, and (D) NIH:OVCAR-3 lysates
using anti-Aromatase RabMAb (cat. #5233-1).

Flow cytometric analysis of permeabilized NIH:OVCAR-3
cells using anti-Aromatase RabMAb (red)
(catalog # 5233-1) or a rabbit IgG (negative) (green).

Specificity

A synthetic peptide corresponding to residues in
human Aromatase was used as an immunogen.

性状 【反应特异性】Human , Rat
【克隆 ID】EPR4534(2)
【用途】WB , FC , IP
【抗原分子量】53kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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