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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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AMPK alpha 1 Phospho (pT183) / AMPK alpha 2 Phospho (pT172) (PRKAA1)
Rabbit Monoclonal Antibody |
| 别 名： |
PRKAA1 antibody, AMPK antibody,
AMPKa1 antibody, MGC33776
antibody, MGC57364 antibody,
5'-AMP-activated protein
kinase catalytic subunit
alpha-1 antibody, antibody |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177530 |
AMPK alpha 1 Phospho (pT183) |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5683
【用途】WB , IP
【抗原分子量】62/63kDa |
| 质量标准： |
【产品介绍】The 5-AMP-activated protein kinase (AMPK),
a member of the SNF1 (sucrose nonfermentor) kinase
family (1) AMPK is a heterotrimeric protein comprising
α (63 kDa), β (38 kDa) and γ (38 kDa) subunits. The
alpha subunit is the catalytic subunit (which
requires phosphorylation to be active) (2-3). Beta and
gamma are noncatalytic subunits, although they have
been found to interact with the active subunit in
liver. AMPK regulates fatty acid and sterol synthesis
by phosphorylation of acetyl-CoA as well as
cholesterol synthesis via phosphorylation and
inactivation of hydroxymethylglutaryl-CoA reductase
(4). AMPK also appears to play a role in protecting
cells from stresses that cause ATP depletion by
switching off ATP-consuming biosynthetic pathways.
Recommended Applications
WB, IP
Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000
IP: 1:10 - 100
Species Reactivity * Human, Mouse, Rat *Cross reactivity determined by western blot only. Products Data
Western blot analysis on 293 cell lysates
using anti-Phospho-AMPK alpha 1/AMPK alpha 2
(pT183/pT172) RabMAb (cat. #3930-1). Cells were
either (A) untreated or (B) treated with Lambda phosphatase. Specificity A phospho specific peptide corresponding to
residues surrounding Threonine 183 of human AMPK alpha 1
and Threonine 172 of human AMPK alpha 2 was used as
an immunogen. This antibody only detects AMPK alpha
1 phosphorylated at Threonine 183 and AMPK alpha
2 phosphorylated Threonine 172. |
| 贮 存： |
Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt |
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