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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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AIF Rabbit Antibody
Rabbit Monoclonal IgG |
| 别 名： |
Programmed cell death protein 8 |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177514 |
AIF Rabbit Antibody |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse , Rat
【克隆 ID】E20
【用途】WB , IHC , ICC , FC , IP
【抗原分子量】67 kDa |
| 质量标准： |
【产品介绍】AIF, o r apoptosis-inducing fact o r , is
a flavoprotein localized to the mitochondrial membrane
that plays a primary role in caspase-independent cell
death, o r apoptosis (1,2). AIF translocates to the
nucleus when apoptosis is induced a n d causes
mitochondria to release the apoptogenic proteins,
cytochrome c a n d caspase-9. Apoptotic activity of
AIF leads to chromatin condensation a n d DNA
fragmentation (1). Similar to cytochrome c, AIF is
a bifunctional protein with an oxid o r eductase function
a n d a second apoptogenic function. In contrast
to cytochrome c, however, AIF acts in a
caspase-independent fashion (2,3,4).
WB: 1:1,000
IHC: 1:500
ICC: 1:500
Flow Cytometry: 1:50
IP: 1:10
A. Western blot analysis of K562 cell lysate using
anti-AIF RabMAb (catalog #1020-1), 1:1,000 dilution.
B. Immunohistochemical analysis of paraffin-embedded
human cervical carcinoma using anti-AIF RabMAb
(catalog #1020-1).
C. Immunoflu o r escent staining of HeLa cells, using
AIF RabMAb. (Green flu o r escence- AIF localized
in mitochondria, Red - PI nuclear staining).
(catalog #1020-1).
D. Flow cytometric analysis of permeabilized K562
cells using anti-AIF RabMAb (red) (catalog #1020-1)
o r a rabbit IgG (negative)(green). |
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