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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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5-Methylcytosine antibody
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| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177498 |
5-Methylcytosine antibody |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse , Rat
【克隆 ID】EP4694
【用途】ICC , ELISA
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| 质量标准： |
【产品介绍】5-Methylcytosine is the methylated form of
the DNA base cytosine. In mammalian cells, DNA
methylation is an enzymatic modification at the
5-position of cytosine present abundantly within the
CpG dinucleotide sequence context. This DNA modification
is inheritable and reversible without primary DNA
base sequence changes resulting in possible
epigenetic modulation of phenotype and gene
expression (1). CpG methylation may directly interfere
with the binding of certain transcriptional regulators
to their cognate DNA sequences or may enable recruitment
of methyl-CpG binding proteins that create a
repressed chromatin environment (2). The de novo
formation and maintenance of 5-methylcytosine is
catalyzed by DNA methyltransferase proteins (DNMTs) (1).
Recommended Applications
MeDIP, ICC, ELISA
Applications and Recommended Dilution Factors MeDIP: 1 - 5 ug/mL
ICC: 1 ug/mL
ELISA: 0.1 ug/ml
Species Reactivity Human, Mouse, Rat Specificity KLH-5-Methylcytosine was used as immunization. |
| 贮 存： |
Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt |
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