5-Methylcytosine antibody

英文名:
Cas号:
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308113299-100ul  现货 0 ¥0 请登录
- +
偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体,下单前请联系客服。
别 名
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】5-Methylcytosine is the methylated form of
the DNA base cytosine. In mammalian cells, DNA
methylation is an enzymatic modification at the
5-position of cytosine present abundantly within the
CpG dinucleotide sequence context. This DNA modification
is inheritable and reversible without primary DNA
base sequence changes resulting in possible
epigenetic modulation of phenotype and gene
expression (1). CpG methylation may directly interfere
with the binding of certain transcriptional regulators
to their cognate DNA sequences or may enable recruitment
of methyl-CpG binding proteins that create a
repressed chromatin environment (2). The de novo
formation and maintenance of 5-methylcytosine is
catalyzed by DNA methyltransferase proteins (DNMTs) (1).


Recommended Applications

MeDIP, ICC, ELISA
Applications and Recommended Dilution Factors

MeDIP: 1 - 5 ug/mL
ICC: 1 ug/mL
ELISA: 0.1 ug/ml
Species Reactivity

Human, Mouse, Rat

Specificity

KLH-5-Methylcytosine was used as immunization.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EP4694
【用途】ICC , ELISA
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。
X
QQ