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Fumitremorgin C

英文名：Fumitremorgin C
Cas号：118974-02-0
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
13081129741-0.25mg 98% 0 ￥2160.4
- +
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别 名 Tryptoquivaline FTC
Cas号 118974-02-0
M D L MFCD08702652
分子式 C22H25N3O3
分子量 379.45
产品参数
性状 Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
贮存 储存温度:−20°C
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